罗晴蓉;李运飞;边林;张丽芳;

• 1:长治医学院
• 2:长治医学院附属长治市人民医院

摘要(Abstract)：

阿替普酶(重组组织型纤溶酶原激活剂,rt-PA)静脉溶栓是目前国内外医治急性缺血性脑卒中(acute ischemic stroke,AIS)最有效的方法之一,其临床疗效已得到广泛验证,然而溶栓后继发出血转化(hemorrhagic transformation,HT)是其并发症之一,严重影响治疗效果及预后。溶栓后HT由多种危险因素引起,国内外很多学者和团队针对可能影响HT的危险因素进行了研究,并且建立了一系列预测模型预测静脉溶栓后HT的风险。本文就rt-PA静脉溶栓后继发HT的病变机制、危险因素及预测模型作一综述。

关键词(KeyWords)： 缺血性脑卒中;静脉溶栓;出血转化;危险因素;预测模型

Abstract:

Keywords:

基金项目(Foundation): 山西省卫生计生委科研项目(编号:201602027)

作者(Authors): 罗晴蓉;李运飞;边林;张丽芳;

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