细胞学检测在小儿结核性脑膜炎中的诊断价值及与病毒性脑膜炎对比研究The diagnostic value of cytology in children with tuberculous meningitis and its comparison with viral meningitis
陈玉霞;
摘要(Abstract):
目的分析小儿结核性脑膜炎、病毒性脑膜炎的诊断中进行细胞学检测的价值。方法选择2013-04—2019-04商丘市第三人民医院收治的结核性脑膜炎患儿20例(结核组),病毒性脑膜炎患儿30例(病毒组)为对象,均进行细胞学检测,比较2组细胞类型、血清白蛋白、脑脊液白蛋白、脑脊液白蛋白指数、血脑屏障损伤程度。结果结核组C_(ALB)与病毒组比较差异无统计学意义(P>0.05),结核组S_(ALB)、C_(ALB)指数明显高于病毒组(P<0.05);结核组小淋巴细胞、淋巴样细胞、转化淋巴细胞均低于病毒组(P<0.05),激活单核细胞、嗜中性粒细胞均高于病毒组脑膜炎患儿(P<0.05),结核组与病毒组浆细胞、单核细胞比重差异无统计学意义(P>0.05);结核组血脑屏障轻度损伤比重为16.67%,明显低于病毒组比重(46.67%),差异有统计学意义(P<0.05),结核组中度损伤与重度损伤比重分别为40.00%、43.33%,均多于病毒组(30.00%、23.33%),但差异无统计学意义(P>0.05)。结论细胞学检测能够帮助鉴别小儿结核性脑膜炎、病毒性脑膜炎,为临床诊疗进行提供科学指导。
关键词(KeyWords): 小儿结核性脑膜炎;病毒性脑膜炎;细胞学检测
基金项目(Foundation):
作者(Authors): 陈玉霞;
参考文献(References):
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