李晶;杨萍;孙永敏;施梦丽;杨洋;

• 1:郑州大学第二附属医院核医学科

摘要(Abstract)：

目的探讨PET-CT在难治性癫痫手术致痫灶定位应用中的准确性。方法回顾性分析80例2016-03—2018-05在郑州大学第二附属医院治疗的难治性癫痫患者,所有患者均已明确口服抗癫痫药物效果较差,经磁共振检查均为阴性,经24h视频脑电监测结果回示有明显异常,根据是否行PET-CT检查分组,其中40例行PET-CT检查的患者设定为观察组,使用神经外科导航融合PET-CT影像学数据行术前定位癫痫灶;未行PET-CT检查的40例患者设定为对照组。2组患者术中均使用皮层脑电图监测定位致痫灶,并通过手术切除癫痫灶,观察术后癫痫症状的缓解情况。结果观察组治疗效果明显优于对照组(P<0.05);且观察组术后癫痫缓解情况、术中损伤明显优于对照组(P<0.05)。结论 PET-CT联合神经外科导航可优化难治性癫痫手术的过程,在整个治疗过程起到关键作用。

关键词(KeyWords)： 难治性癫痫;PET-CT;神经导航;癫痫灶;术中皮层脑电

Abstract:

Keywords:

基金项目(Foundation): 河南省医学科技攻关计划项目(编号：201503092)

作者(Authors): 李晶;杨萍;孙永敏;施梦丽;杨洋;

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