李春;赵高峰;滕军放;

• 1:郑州大学第一附属医院神经内科
• 2:郑州市第三人民医院神经内科

摘要(Abstract)：

目的探讨中性粒细胞/淋巴细胞比值及空腹血糖在脑出血患者短期死亡评估中的作用。方法选取2016-06-01—2018-05-31在郑州大学第一附属医院神经内科住院诊疗的189例急性脑出血患者为研究对象,选取同期健康体检者189例为参照组,单因素分析2组临床及实验室资料;发病30d时统计生存与死亡人数,分为生存组与死亡组,单因素分析2组临床、影像学及实验室资料,采用多因素Logistic回归分析统计影响急性脑出血短期死亡的危险因素,采用受试者工作特征(receiver operating characteristic,ROC)曲线评价NLR和FBG对短期死亡的预测价值。结果急性脑出血组与对照组比较,NLR(5.67±1.53vs 4.01±1.53)和FBG(7.07±2.47vs 5.59±1.89)差异有统计学意义(P<0.05);死亡组与存活组比较,NLR(6.82±1.04vs 5.52±1.46)和FBG(10.06±2.51vs 6.69±2.21)差异有统计学意义(P<0.05);多因素Logistic回归分析显示,WBC、FBG、NLR、GCS与急性脑出血发病30d时的死亡独立相关(P<0.05);ROC曲线分析表明,NLR和FBG的ROC曲线下面积(AUC)分别为0.777(95%CI:0.667～0.877,P<0.01)、0.864(95%CI:0.792～0.937,P<0.01)。结论 NLR和FBG是预测急性脑出血患者短期死亡的独立危险因素。

关键词(KeyWords)： 急性脑出血;中性粒细胞与淋巴细胞比值;空腹血糖;死亡;危险因素

Abstract:

Keywords:

基金项目(Foundation): 国家自然科学基金面上项目(编号：81671267)

作者(Authors): 李春;赵高峰;滕军放;

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