偏头痛与血管周围间隙的相关性研究进展
贾艳露;李慧;刘春岭;
摘要(Abstract):
偏头痛是一种原发性,以反复发作的伴自主神经功能障碍为主要临床特征的慢性神经血管功能障碍性疾病。其发病机制目前尚不清楚,临床上会导致多种并发症,尤其是神经精神系统疾病的发生。该病缺乏特异的影像学特征,其在磁共振上可表现为脑白质异常、血管周围间隙数目增多或扩大等影像学改变。其中血管周围间隙的改变属于脑小血管病,与神经系统疾病也有着一定的关联。目前,关于偏头痛、血管周围间隙的研究进展以及两者之间关系的相关报道日益增多,本综述总结了偏头痛、血管周围间隙扩大的发病机制;两者引起常见并发症的病理机制以及两者之间的相互关系,以期临床上对其有更多的关注、认识和研究。
关键词(KeyWords): 偏头痛;血管周围间隙;脑卒中;认知功能障碍;发病机制
基金项目(Foundation): 河南省科技攻关项目(编号:20130138)
作者(Authors): 贾艳露;李慧;刘春岭;
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