转甲状腺素蛋白与神经系统疾病的关系研究进展Research progress on the relationship between transthyretin and neurological diseases
王凤君;李伟;
摘要(Abstract):
转甲状腺素蛋白(transthyretin,TTR),一种同源四聚体蛋白,因其电泳迁移恰好在白蛋白之前,故命名为前白蛋白(prealbumin,PA)。TTR对大脑的生长、发育功能有着重要作用,很多学者开始研究其与缺血性脑卒中的严重程度及预后、抑郁症、阿尔茨海默病(alzheimer’s disease,AD)及淀粉样变性病的相关性。本文就TTR在中枢神经系统疾病的临床意义及研究进展作一综述。
关键词(KeyWords): 转甲状腺素蛋白;中枢神经系统;缺血性脑卒中;抑郁症;阿尔茨海默病;淀粉样变性病
基金项目(Foundation): 陕西省科学技术研究发展计划项目(编号:S2015YFSF0325)
作者(Authors): 王凤君;李伟;
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