林秋红;蔡伦;周艳英;

• 1:广西中医药大学第一附属医院

摘要(Abstract)：

目的比较急性炎症性脱髓鞘性多发性神经病(AIDP)与慢性炎症性脱髓鞘性多发性神经病急性起病(A-CIDP)成年患者的临床和电生理特点。方法收集AIDP或A-CIDP患者44例(AIDP,n=30;A-CIDP,n=14)。分析人口学特征、临床表现、脑脊液特点、电生理检测特点。结果 AIDP与A-CIDP患者多见于男性(53%vs 72%,P=0.33),AIDP具有糖尿病病史患者比例相对较低(3%vs 28%,P=0.03),脑神经功能障碍较多见(56%vs 14%,P=0.01),从发病进展到病情最高峰的时间较短(8.2d vs 18.2d,P=0.04);MRC总分均值较低(40 vs 50,P=0.01),mNCV减慢的百分比较低(33%vs 71%,P=0.04)。结论发病进展到病情最严重时间为8 d左右,表现有脑神经功能障碍,MRC总分较低,mNCV减慢比例较低且有轴索损伤,应考虑诊断AIDP,反之则考虑A-CIDP。

关键词(KeyWords)： 急性炎症性脱髓鞘性多发性神经病;慢性炎症性脱髓鞘性多发性神经病;神经功能障碍;糖尿病;电生理检测

Abstract:

Keywords:

基金项目(Foundation): 广西自然科学基金项目(编号:2015GXNSFBA139172);; 广西中医药大学第一附属医院学术团队建设项目(编号:院字[2018]146号);广西中医药大学“岐黄工程”高层次人才团队培育项目(编号:2018003);; 卫生人才队伍建设-广西医学高层次骨干人才培养“139”计划

作者(Authors): 林秋红;蔡伦;周艳英;

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