董留建;冯书彬;冯强;吕强;李涛;裴航;齐林;

• 1:河南省儿童医院郑州儿童医院

摘要(Abstract)：

目的分析儿童先天性脑积水手术前后认知功能变化。方法回顾性分析2017-01—2020-01河南省儿童医院收治的120例先天性脑积水患儿的临床资料,其中ETV组65例,VPS组55例,ETV组进行第三脑室底造瘘术(ETV),VPS组采用脑室-腹腔分流术(VPS)。术后随访6个月,观察2组患者手术情况及术后随访情况,分析手术前后患儿认知功能改善情况。结果 ETV组手术时间、术后排气时间均明显低于VPS组(P<0.05)。手术前后2组双侧脑室额角差值均较小(P>0.05)。术后随访6个月2组总有效率比较差异无统计学意义(P>0.05)。2组Kamofsky评分同期比较差异无统计学意义(P>0.05),2组术后Kamofsky评分均较术前显著升高(P<0.05)。术后VPS组分流管梗阻和腹腔感染发生率均显著高于ETV组(P<0.05),ETV组和VPS组患儿术后6个月发育商(DQ)高于术前且ETV组高于VPS组(P<0.05)。结论先天性脑积水患儿在进行ETV和VPS手术后病情和认知功能均能够得到有效改善,ETV术后并发症概率高于VPS组且认知功能障碍改善情况优于VPS组。

关键词(KeyWords)： 先天性脑积水;第三脑室底造瘘术;脑室-腹腔分流术;认知功能障碍

Abstract:

Keywords:

基金项目(Foundation): 河南省医学科技攻关计划联合共建项目（编号：LHGJ20190942）

作者(Authors): 董留建;冯书彬;冯强;吕强;李涛;裴航;齐林;

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