谢凯凯;曹文锋;项正兵;刘世民;饶伟;吴凌峰;

• 1:江西省人民医院
• 2:南昌大学医学院

摘要(Abstract)：

目的探讨急性前循环大血管闭塞时桥接治疗和单纯机械取栓治疗的临床疗效及安全性。方法回顾性分析2016-08—2019-10收住江西省人民医院神经内科的急性前循环大血管闭塞并行机械取栓或桥接治疗的患者55例,其中25例为桥接治疗,30例为单纯机械取栓治疗。通过比较2组患者基线资料、有效再灌注率、中位取栓次数、治疗有效率、并发症、院内死亡及功能结局(改良mRS评分),评估两种治疗方案的有效性和安全性。结果机械取栓组除高血压患病率较高(P=0.012)和起病至入院的时间较长(P<0.001)外,其余基线资料与桥接组比较无显著差异(P>0.05)。与治疗前相比,2组的再灌注率、治疗有效率、良好功能结局均明显上升(P<0.05),但2组间无显著性差异(P>0.05)。余2组在中位取栓次数、并发症、住院时间、住院费用、院内死亡和出院后90d的全因死亡无显著性差异(P>0.05)。结论以支架取栓为基础的血管内治疗可为患者带来显著的临床疗效,对于因错过静脉溶栓时间窗或有其他静脉溶栓禁忌患者,单纯机械取栓治疗具有和桥接治疗相似临床疗效及安全性。

关键词(KeyWords)： 急性脑梗死;机械取栓;桥接治疗;血管内治疗;前循环大血管闭塞

Abstract:

Keywords:

基金项目(Foundation): 江西省重点科技成果转移转化计划(编号:20161BBI90050);; 江西省卫生计生委科技计划(编号:20175018)

作者(Authors): 谢凯凯;曹文锋;项正兵;刘世民;饶伟;吴凌峰;

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