急性椎基底动脉闭塞机械再通疗效分析The efficacy and safety of mechanical thrombectomy for acute vertebrobasilar artery occlusion
孟飞龙;徐浩文;权涛;袁永杰;王子博;高飞;管生;
摘要(Abstract):
目的分析急性椎基底动脉闭塞行机械再通的可行性和安全性及评价预后影响因素。方法回顾性收集2012-01-2019-07在郑州大学第一附属医院神经介入科收治的急性椎基底动脉闭塞行机械再通146例患者的临床资料,根据治疗3个月后mRS评分,分为预后良好组(0~2分)和预后不良组(3~6分)。分析2组的临床数据与不同预后之间的关系。结果共110例患者纳入本研究,再通成功率(mTICI≥2b)为86.4%(95/110),预后良好率(mRS≤2)48.2%(53/110)。2组年龄、入院NIHSS评分、合并高血压、从发病至股动脉穿刺及手术时间、术后即刻再通效果(mTICI分级)及合并症状性脑出血比较差异均有统计学意义(P值分别为0.006、0.000、0.000、0.037、0.007、0.025、0.001),其余资料差异均无统计学意义(P>0.05)。结论血管内介入治疗急性椎基底动脉闭塞性脑卒中有较高的再通率和预后良好率。高龄、入院高NIHSS评分、高血压史、从发病至股动脉穿刺以及手术时间长、术后即刻再通效果和症状性脑出血与预后不良相关。
关键词(KeyWords): 急性脑卒中;椎基底动脉闭塞;机械再通;危险因素
基金项目(Foundation): 国家重点研发计划2018年定向项目,编号:2018YFC1311303
作者(Authors): 孟飞龙;徐浩文;权涛;袁永杰;王子博;高飞;管生;
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