高分辨C臂CT联合3D-DSA双容积重建融合技术在颅内动脉瘤血流导向装置(Tubridge)置入术贴壁评估中的初步应用Clinical study of high-resolution C-arm CT with 3D-DSA dual-volume fusion reconstruction technique in flow diverter(Tubridge)implantation of intracranial aneurysms
付培基;李腾飞;马骥;朱明;朱涛;马宝;韩新巍;
摘要(Abstract):
目的探讨高分辨C臂CT技术联合三维DSA血管成像(3D-DSA)双容积重建融合技术在颅内动脉瘤国产血流导向装置(Tubrige Flow Diverter,Tubrige FD)置入术贴壁评估中的应用价值。方法回顾性分析2019-01—2019-04郑州大学第一附属医院放射介入科连续收治的39例颅内动脉瘤采用Tubridge FD治疗患者的临床及影像学资料,使用西门子DSA后处理工作站将术中FD置入区域20s高分辨C臂CT(Dyna micro CT)扫描结果和5s3D-DSA血管成像结果进行双容积重建并融合,融合图像采用多种后处理技术(如高级三维容积漫游-VRT,最大密度投影-MIP等)动态观察支架贴壁情况,并与载瘤动脉内注射稀释对比剂后20sDyna micro CT扫描重建图像对比,评估前者在判断FD贴壁方面的准确性。结果 39例动脉瘤患者共置入39枚Tubridge FD,其中10例患者联合弹簧圈填塞治疗。在支架贴壁方面,二种技术各自独立检出8例患者FD贴壁不良,31例贴壁良好,一致率100%,其中贴壁不良8例患者采用"massage"技术,即微导丝成袢支架内促使贴壁或球囊扩张处理后支架贴壁良好。结论高分辨C臂CT技术联合3D-DSA双容积重建融合技术能清晰展示Tubridge FD贴壁情况并指导术者采取相应的治疗策略,这种新颖的成像技术在颅内动脉瘤FD置入中具有较大应用前景。
关键词(KeyWords): C臂CT;颅内动脉瘤;双容积融合技术;血流导向装置;影像融合
基金项目(Foundation): 国家自然科学基金资助项目(编号:81801806)
作者(Authors): 付培基;李腾飞;马骥;朱明;朱涛;马宝;韩新巍;
参考文献(References):
- [1]ALTES T A,CLOFT H J,SHORT J G,et al.1999ARRS Executive Council Award.Creation of saccular aneurysms in the rabbit:a model suitable for testing endovascular devices.American Roentgen Ray Society[J].AJR Am J Roentgenol,2000,174(2):349-354.DOI:10.2214/ajr.174.2.1740349.
- [2]AQUARIUS R,DE KORTE A,SMITS D,et al.The Importance of Wall Apposition in Flow Diverters[J].Neurosurgery,2019,84(3):804-810.DOI:10.1093/neuros/nyy092.
- [3]LIANG F,ZHANG Y,YAN P,et al.Outcomes and Complications After the Use of the Pipeline Embolization Device in the Treatment of Intracranial Aneurysms of the Posterior Circulation:A Systematic Review and Meta-Analysis[J].World Neurosurg,2019,127:e888-e895.DOI:10.1016/j.wneu.2019.03.291.
- [4]YUKI I,KAMBAYASHI Y,IKEMURA A,et al.HighResolution C-Arm CT and Metal Artifact Reduction Software:A Novel Imaging Modality for Analyzing Aneurysms Treated with Stent-Assisted Coil Embolization[J].AJNR Am J Neuroradiol,2016,37(2):317-323.DOI:10.3174/ajnr.A4509.
- [5]O'KELLY C J,KRINGS T,FIORELLA D,et al.A novel grading scale for the angiographic assessment of intracranial aneurysms treated using flow diverting stents[J].Interv Neuroradiol,2010,16(2):133-137.DOI:10.1177/159101991001600204.
- [6]韩新巍,水少锋.神经血管疾病介入治疗与研究进展[M].郑州:郑州大学出版社,2017:78.
- [7]ZHANG Y,HUANG QH,FANG Y,et al.A Novel Flow Diverter(Tubridge)for the Treatment of Recurrent Aneurysms:A Single-Center Experience[J].Korean JRadiol,2017,18(5):852-859.DOI:10.3348/kjr.2017.18.5.852.
- [8]FANG Y B,WEN W L,YANG P F,et al.Long-Term Outcome of Tubridge Flow Diverter(S)in Treating Large Vertebral Artery Dissecting Aneurysms-A Pilot Study[J].Clin Neuroradiol,2017,27(3):345-350.DOI:10.1007/s00062-015-0494-8.
- [9]ZHOU Y,YANG P F,FANG Y B,et al.Parent artery reconstruction for large or giant cerebral aneurysms using a Tubridge flow diverter(PARAT):study protocol for a multicenter,randomized,controlled clinical trial[J].BMC Neurol,2014,14:97.DOI:10.1186/1471-2377-14-97.
- [10]KATO N,YUKI I,ISHIBASHI T,et al.Visualization of stent apposition after stent-assisted coiling of intracranial aneurysms using high resolution 3Dfusion images acquired by C-arm CT[J].J Neurointerv Surg,2020,12(2):192-196.DOI:10.1136/neurintsurg-2019-014966.
- [11]HARIHARAN S G,KAETHNER C,STROBEL N,et al.Preliminary results of DSA denoising based on a weighted low-rank approach using an advanced neurovascular replication system[J].Int J Comput Assist Radiol Surg,2019,14(7):1117-1126.DOI:10.1007/s11548-019-01968-4.
- [12]SHINOHARA Y,SAKAMOTO M,IWATA N,et al.Usefulness of monochromatic imaging with metal artifact reduction software for computed tomography angiography after intracranial aneurysm coil embolization[J].Acta Radiol,2014,55(8):1015-1023.DOI:10.1177/0284185113510492.
- [13]KATSURA M,SATO J,AKAHANE M,et al.Singleenergy metal artifact reduction technique for reducing metallic coil artifacts on post-interventional cerebral CTand CT angiography[J].Neuroradiology,2018,60(11):1141-1150.DOI:10.1007/s00234-018-2081-6.
- [14]HELLER R,CALNAN D R,LANFRANCHI M,et al.Incomplete stent apposition in Enterprise stentmediated coiling of aneurysms:persistence over time and risk of delayed ischemic events[J].J Neurosurg,2013,118(5):1014-1022.DOI:10.3171/2013.2.JNS121427.
- [15]ZHANG H,GAO X,LIANG H,et al.Incomplete stent apposition of low-profile visualized intraluminal support stents in the treatment of cerebral aneurysms[J].J Neurointerv Surg,2020,12(6):591-597.DOI:10.1136/neurintsurg-2019-015505.
- [16]AQUARIUS R,DE KORTE A,SMITS D,et al.The Importance of Wall Apposition in Flow Diverters[J].Neurosurgery,2019,84(3):804-810.DOI:10.1093/neuros/nyy092.
- [17]LI T F,MA J,HAN X W,et al.Application of HighResolution C-Arm CT Combined with Streak Metal Artifact Removal Technology for the Stent-Assisted Embolization of Intracranial Aneurysms[J].AJNR Am J Neuroradiol,2019,40(10):1752-1758.DOI:10.3174/ajnr.A6190.
- [18]YUKI I,ISHIBASHI T,DAHMANI C,et al.Combination of high-resolution cone beam computed tomography and metal artefact reduction software:a new image fusion technique for evaluating intracranial stent apposition after aneurysm treatment[J].BMJCase Rep,2019,12(9):e230687.DOI:10.1136/bcr-2019-230687.
- [19]ZHANG Q,ZHAO H,SUN Q,et al.Clinical evaluation of volume of interest imaging combined with metal artifact reduction reconstruction techniques in coiling and stent assisted coiling during neurointerventional procedures[J].J Neurointerv Surg,2019,11(2):205-210.DOI:10.1136/neurintsurg-2018-013886.
- [20]MURAI S,HIRAMATSU M,TAKASUGI Y,et al.Metal artifact reduction algorithm for image quality improvement of cone-beam CT images of medium or large cerebral aneurysms treated with stent-assisted coil embolization[J].Neuroradiology,2020,62(1):89-96.DOI:10.1007/s00234-019-02297-8.
- [21]SRINIVASAN V M,CHINTALAPANI G,CAMSTRA KM,et al.Fast acquisition cone-beam computed tomography:initial experience with a 10sprotocol.J Neurointerv Surg.2018,10(9):916-920.DOI:10.1136/neurintsurg-2017-013475.
- [22]CAROFF J,MIHALEA C,NEKI H,et al.Role of C-arm VasoCT in the use of endovascular WEB flow disruption in intracranial aneurysm treatment[J].AJNRAm J Neuroradiol,2014,35(7):1353-1357.DOI:10.3174/ajnr.A3860.
- [23]JING L,ZHONG J,LIU J,et al.Hemodynamic Effect of Flow Diverter and Coils in Treatment of Large and Giant Intracranial Aneurysms[J].World Neurosurg.2016,89:199-207.DOI:10.1016/j.wneu.2016.01.079.
- [24]ZHANG Y,HUANG Q H,FANG Y,et al.A Novel Flow Diverter(Tubridge)for the Treatment of Recurrent Aneurysms:A Single-Center Experience[J].Korean J Radiol,2017,18(5):852-859.DOI:10.3348/kjr.2017.18.5.852.
- [25]ZHANG X,LV N,WANG C,et al.Late recurrence of a completely occluded large intracranial aneurysm treated with a Tubridge flow diverter[J].J Neurointerv Surg,2017,9(2):e6.DOI:10.1136/neurintsurg-2016-012268.rep.
- [26]DELGADO ALMANDOZ J E,KAYAN Y,TENREIROA,et al.Clinical and angiographic outcomes in patients with intracranial aneurysms treated with the pipeline embolization device:intra-procedural technical difficulties,major morbidity,and neurological mortality decrease significantly with increased operator experience in device deployment and patient management[J].Neuroradiology,2017,59(12):1291-1299.DOI:10.1007/s00234-017-1930-z.
- [27]KALLMES D F,BRINJIKJI W,CEKIRGE S,et al.Safety and efficacy of the Pipeline embolization device for treatment of intracranial aneurysms:a pooled analysis of 3large studies[J].J Neurosurg,2017,127(4):775-780.DOI:10.3171/2016.8.JNS16467.