脑出血急性期血常规参数的变化与预后的关系The relationship between the changes of blood routine parameters and the prognosis of patients with acute cerebral hemorrhage
吴幸;
摘要(Abstract):
目的分析脑出血急性期血常规参数的变化与预后的关系。方法将103例脑出血急性期患者纳入研究,30例健康检查者为正常组。脑出血急性期患者分组:按出血情况不同分为血肿扩大组、并发脑室出血组、出血量<30mL组、出血量≥30mL组,对比淋巴细胞计数、白细胞计数、中性粒细胞计数;按格拉斯哥昏迷指数(GCS)分为重度组、中度组和轻度组,对比急性期不同时间白细胞计数和中性粒细胞计数;按预后分为死亡、不良和良好组,对比白细胞计数和中性粒细胞计数。使用Logistic回归分析中性粒细胞、白细胞与脑出血急性期预后的关系及预测预后有效率。结果出血量<30mL组淋巴细胞与正常组差异无统计学意义(P>0.05),脑出血组白细胞、中性粒细胞计数与对照组比较差异有统计学意义(P<0.05);并发脑室出血患者中性粒细胞计数及白细胞计数均明显高于出血量<30 mL患者(P<0.05),但淋巴细胞计数差异无统计学意义(P>0.05)。入院时、入院后3d、7d,轻、中、重组白细胞计数及中性粒细胞计数差异有统计学意义(P<0.05),治疗15d这种差异消失。死亡者白细胞计数及中性粒细胞计数最高(P<0.05)。脑积血患者白细胞计数上升77.14%,中性粒细胞上升71.43%。结论脑出血急性期外周血白细胞计数和淋巴细胞计数不仅与病情严重程度有关,还与出血量、治疗时间相关,是评估预后的重要指标。
关键词(KeyWords): 白细胞计数;中性粒细胞计数;脑出血急性期;淋巴细胞计数;预后
基金项目(Foundation): 河南省医学科技攻关计划项目(201404H007)
作者(Authors): 吴幸;
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