颈动脉斑块内新生血管与血压及血压变异的相关性分析Correlation analysis of neovascularization in hypoechoic carotid plaque with blood pressure and blood pressure variability
郑叶祥,石智锋,马恒章,林细容,李冠夏,郑志雄,陈茂玉
摘要(Abstract):
目的探讨血压及血压变异与斑块内新生血管(NV)的关系。方法入组颈动脉低回声斑块及行超声造影检查患者,分为斑块内无NV组(N-NV组)和斑块内NV组。连续监测每日血压,计算血压变异系数(BP-CV),规范化表格收集人口特征及临床资料。结果 (1)入组患者84例,平均年龄64.3岁,斑块内NV检出率70.2%;(2)NV组与N-NV组性别、SBPmean、DBPmean及DBPcv比较差异有统计意义(P<0.05);(3)Logistic回归分析发现,校正所有变量后,SBPmean、DBPmean及DBPcv与斑块NV风险呈正相关,差异有统计统计学意义(P<0.05),比值比分别为:OR=1.104,95%CI(1.036,1.175);OR=1.285,95%CI(1.115,1.481)和OR=1.261,95%CI(1.018,1.561)。结论血压及血压变异与斑块内新生血管均相关,提示不稳定斑块防治应重视血压及血压变异控制。
关键词(KeyWords): 血压;血压变异;斑块内新生血管;超声造影
基金项目(Foundation): 福建省自然科学基金(编号:2016J01659)
作者(Author): 郑叶祥,石智锋,马恒章,林细容,李冠夏,郑志雄,陈茂玉
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