段佩;蔡远坤;杨超;邵钰阳;江普查;

• 1:武汉大学中南医院

摘要(Abstract)：

目的筛选动脉瘤术后发生分流依赖性脑积水(shunt-dependent hydrocephalus,SDH)的危险因素,为动脉瘤术后SDH临床治疗提供指导意见。方法回顾性分析2019-01—2019-12在中南医院神经外科接受治疗的246例动脉瘤手术患者的相关临床资料,按是否并发SDH分为SDH组(27例)和非SDH组(219例),对2组患者的临床相关资料行单因素分析,并将有显著性差异的结果纳入多因素logistic回归分析,探讨发生SDH的危险因素。结果单因素分析显示,入院GCS评分、Hunt-Hess分级、改良Fisher分级、持续脑脊液引流、动脉瘤破裂、术前急性脑积水、动脉瘤的部位、动脉瘤的大小及去骨瓣减压与SDH的发生密切相关(P<0.05)。多因素logistic回归分析显示,持续脑脊液引流(OR=3.928,95%CI:1.235～12.496)、Hunt-Hess分级(Ⅲ～Ⅴ级)(OR=6.034,95%CI:1.349～26.988)、动脉瘤部位(后循环)(OR=0.317,95%CI:0.103～0.976)是动脉瘤术后发生SDH的独立危险因素(P<0.05)。结论 SDH是动脉瘤术后常见的严重并发症,其危险因素包括持续脑脊液引流、高Hunt-Hess分级(Ⅲ～Ⅴ级)、后循环动脉瘤。合并这些危险因素的病人应特别关注,可针对不同病人采取个体化措施减少术后分流依赖性脑积水的发生。

关键词(KeyWords)： 脑积水;动脉瘤;分流依赖;危险因素

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 段佩;蔡远坤;杨超;邵钰阳;江普查;

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