刘涛,陈硕,冯艳蓉

• 1:东南大学医学院附属南京同仁医院神经内科

摘要(Abstract)：

目的提高对妊娠、流产致视神经脊髓炎谱系疾病(NMOSD)复发相关性认识。方法报道1例妊娠、流产后导致APQ4抗体阴性的NMOSD复发患者,结合文献复习进行分析。结果该例患者为妊娠、流产后导致NMOSD复发,查血清及脑脊液APQ4抗体、MOG抗体均阴性,诊断APQ4抗体阴性的NMOSD明确。经激素及免疫球蛋白等治疗,预后良好。结论 NMOSD与妊娠、流产关系密切,两者相互影响。本病例APQ4抗体、MOG抗体阴性,说明复发除与APQ4抗体、MOG抗体有关外,尚有其他可能的发病机制。

关键词(KeyWords)： 妊娠;流产;视神经脊髓炎谱系疾病;水通道蛋白4(APQ4)抗体;髓鞘少突胶质细胞糖蛋白(MOG)抗体;相关性

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 刘涛,陈硕,冯艳蓉

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