脑白质疏松症的临床危险因素分析Clinical analysis of risk factors of leukoaraiosis
何敏;陈后勤;邵凌云;张强;
摘要(Abstract)：
目的探讨脑白质疏松症的临床危险因素。方法回顾性分析2015-01-01—2016-06-01连续收治的116例脑白质疏松症患者的临床资料,利用脑白质疏松症Fazekasz量表评分将LA患者分为中度组(n=70)和重度组(n=46),并对其临床资料进行统计学处理。结果脑白质疏松症合并高血压史85例(73.2%),糖尿病15例(12.9%),脂代谢异常76例(65.5%),大动脉粥样硬化63例(54.3%),平均同型半胱氨酸水平为21.98mg/L。与中度组相比,重度组年龄较大,胆固醇、低密度脂蛋白、载脂蛋白A及载脂蛋白B的水平更低(P<0.05);而同型半胱氨酸水平更高(P<0.05)。结论年龄、高血压、脂代谢异常、同型半胱氨酸水平等因素均与LA的发生有关;其中高龄和高同型半胱氨酸与LA的发生有关,而血胆固醇、低密度脂蛋白及载脂蛋白A、B为LA的保护因素,其降低与更高的Fazekasz量表评分有关。
关键词(KeyWords)： 脑白质疏松症;危险因素;脂代谢异常
基金项目(Foundation):
作者(Authors): 何敏;陈后勤;邵凌云;张强;
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