MRS在界定脑胶质瘤病理级别和病变范围中的诊断价值
王新伟;赵智伟;
摘要(Abstract)：
目的探讨氢质子磁共振波谱成像(MRs)在界定脑胶质瘤病理级别和病变范围中的诊断价值。方法回顾分析2013-11—2016-09经临床或病理证实为脑肿瘤的患者25例,包含低级别胶质瘤10例与高级别胶质瘤15例,对所有患者实施MRS鉴别,分析其鉴别情况。结果所有肿瘤患者的实质中心区与正常者相比均表现出N-乙酰天门冬氨酸(NAA)与肌酸(Cr)降低,而胆碱复合物(Cho)峰升高,出现高级别胶质瘤7例;不同肿瘤患者实质中心区、囊变区及瘤周水肿区的NAA/Cho值均低于正常值,差异均有统计学意义(P<0.05);高级别胶质瘤实质中心区、囊变区及瘤周水肿区间的NAA/Cho值比较,差异有统计学意义(P<0.05);转移瘤实质中心区、囊变区及瘤周水肿区的NAA/CHO值两两比较,差异均有统计学意义(P<0.05);低级别胶质瘤与高级别胶质瘤间的实质中心区、囊变区及瘤周水肿区NAA/Cho值比较,差异均有统计学意义(P<0.05)。结论MRS可较准确界定脑胶质瘤侵润边界,值得普及。
关键词(KeyWords)： MRS;脑胶质瘤;病变范围
基金项目(Foundation):
作者(Authors): 王新伟;赵智伟;
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