正常人汉字工作记忆功能磁共振脑激活区改变的研究Study of Chinese character working memory on the brain activation area by using function magnetic resonance in healthy persons
张斌;张杰文;张淑玲;张道培;付胜奇;张红菊;
摘要(Abstract):
目的探讨正常人汉字任务下脑激活区的改变。方法对40例正常人进行汉字工作记忆功能磁共振扫描。结果汉字工作记忆任务下,编码、保持及提取期均有额叶、楔前叶、楔叶、边缘叶及扣带回的正向激活,且有侧脑室及脑脊液在编码及保持期的正向激活和在提取期的负向激活。除共同激活脑区外,编码期所有激活脑区均为正向激活,保持期正向激活脑区有中央前回、杏仁核、上后扣带皮层(BA 31),负向激活脑区有颞中回、顶叶、角回,提取期正向激活脑区有尾状核。结论汉字任务下,脑激活区的改变除皮层及皮层下结构,还有侧脑室及脑脊液的激活。
关键词(KeyWords): 汉字工作记忆;功能磁共振;脑激活区
基金项目(Foundation): 国家“863”计划资助项目(2012AA011603);; 河南省科学技术厅科技计划项目(132102610197,1321023100633);; 河南省卫生厅重大科技项目(201202023)
作者(Authors): 张斌;张杰文;张淑玲;张道培;付胜奇;张红菊;
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