谢民;李映霞;武志;郑茂华;

• 1:兰州大学第一医院

摘要(Abstract)：

目的探讨脑疝患者开颅去骨瓣减压术后置入颅内压(ICP)监测的价值。方法对兰州大学第一医院神经外科2016-07—2020-06急诊脑疝患者进行回顾性队列研究,将置入ICP监测与未置入ICP监测的患者按比例1∶1进行倾向得分匹配(PSM)。主要结局指标是90 d的病死率,次要结局指标为住院病死率、颅内感染率、脱水治疗使用次数、90 d(mRS)评分、优秀结果(mRS评分0～1)、良好结果(mRS评分0～2)和住院时间。结果 ICP监测组和无ICP监测组分别有90例和127例患者。PSM前ICP监测组有较高的90 d病死率(45.6%vs 32.3%,P=0.048)、住院病死率(23.3%vs 11.0%,P=0.017)、脱水药物的使用、更长的住院时间中位数(29 d vs 20 d,P=0.02),PSM后2组各有50例患者。ICP监测组和无ICP监测组90 d的病死率、住院病死率、颅内感染率及90 d(mRS)评分:优秀结果(评分0～1)、良好结果(评分0～2)和住院时间对比差异无统计学意义(P>0.05)。结论脑疝患者去骨瓣减压术后颅内压监测与未行颅内压监测患者预后无明显差异。

关键词(KeyWords)： 脑疝;去骨瓣减压术;开颅术;颅内压监测;倾向得分匹配;预后

Abstract:

Keywords:

基金项目(Foundation): 甘肃省科技厅-科技计划项目-创新基地和人才计划(编号:20JR10RA687)

作者(Authors): 谢民;李映霞;武志;郑茂华;

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