特发性震颤的个体化治疗
杨芬;张英谦;吕强;张卫清;赵发国;王姮;宋琛;胡文娟;石进;
摘要(Abstract):
目的探讨特发性震颤的个体化治疗方案。方法选择于我院神经内科门诊就诊的特发性震颤患者120例,依据个体化特点,制定不同的治疗方案,并随访6周。治疗前后进行震颤分级量表评分,同时使用药物副反应量表评定不良反应。结果 46例患者因震颤轻微未治疗;21例患者因震颤仅影响工作,予以临时性治疗(其中应用小剂量酒精4例,普萘洛尔11例,阿罗洛尔6例);53例因震颤影响日常生活及工作接受长期药物治疗(其中应用普萘洛尔14例,阿罗洛尔18例,普拉克索9例,托吡酯12例)。接受长期药物治疗的特发性震颤患者,治疗后震颤评分明显下降,差异有统计学意义(P<0.05)。治疗过程中2例发生低血压,1例出现幻觉,药物减量后消失。结论根据不同特发性震颤患者的具体因素,选择个体化治疗方案,疗效满意。
关键词(KeyWords): 特发性震颤;个体化治疗
基金项目(Foundation):
作者(Authors): 杨芬;张英谦;吕强;张卫清;赵发国;王姮;宋琛;胡文娟;石进;
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