基于MEWS的急性脑卒中短期预后评分系统的构建及评价Construction and evaluation of short-term prognosis scoring system for acute stroke based on MEWS
胡萍;崔妙玲;蒋云;
摘要(Abstract):
目的通过对影响急性脑卒中短期预后的临床危险因素的研究,并联合MEWS,构建急性脑卒中短期预后预测评分系统,为临床治疗和短期预后预测提供依据。方法回顾性研究广西医科大学第一附属医院2018年1月至2018年12月首次诊断急性脑卒中成人患者200例,随访30天,并按临床结局分为预后良好组及预后不良组。收集入院时可能影响患者短期预后相关的危险因素,应用单因素及多因素Logistic逐步向前法确定影响预后的临床危险因素,并根据OR值及β系数建立危险因素模块,与MEWS联合建立预后预测评分系统,最终应用ROC曲线检验其预测效能。结果 (1)单因素分析显示,2组间年龄、白细胞水平、尿酸、红细胞分布宽度、入院血糖及CRP比较差异有统计学意义(P<0.05)。(2)采用Logistic回归筛选出影响急性脑卒中预后独立危险因素:年龄、白细胞、CRP,并进行赋值,联合MEWS形成脑卒中短期预后预测评分系统。(3)经ROC曲线分析,ROC曲线下面积为0.816(P<0.001),且当评分为7分时,预测效能最强。结论 (1)年龄、入院时白细胞计数及CRP水平是影响急性脑卒中预后不良的独立危险因素。(2)预后预测评分系统可较为准确的预测急性脑卒中患者的预后。
关键词(KeyWords): 急性脑卒中;短期预后;相关因素;预后预测;评分系统
基金项目(Foundation):
作者(Authors): 胡萍;崔妙玲;蒋云;
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