奥卡西平 拉莫三嗪 左乙拉西坦对癫痫患者脑电图的影响Effect of oxcarbazepine,lamotrigine and levetiracetam on electroencephalogram in epileptic patients
叶兴荣;朱军;顾卫霞;俞有来;
摘要(Abstract):
目的探讨抗癫痫新药奥卡西平(OXC)、拉莫三嗪(LGT)、左乙拉西坦(LEV)对癫痫患者脑电图的影响。方法对单用奥卡西平、拉莫三嗪、左乙拉西坦的癫痫患儿作服药前及服药后动态脑电图比较。结果奥卡西平、拉莫三嗪、左乙拉西坦均可使癫痫患儿脑电图痫性活动减少,但拉莫三嗪、左乙拉西坦优于奥卡西平;奥卡西平组易发生背景波减慢,α活动减少,θ、δ增多,但拉莫三嗪、左乙拉西坦影响较小。结论拉莫三嗪、左乙拉西坦对脑电图不良影响较小,有利于控制痫性活动,更易达到停药标准。
关键词(KeyWords): 癫痫;药物疗法;脑电图;奥卡西平;拉莫三嗪;左乙拉西坦
基金项目(Foundation): 2015扬州市重点研发计划-社会发展项目,编号:YZ2015051
作者(Authors): 叶兴荣;朱军;顾卫霞;俞有来;
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