王彦阔;焦淑洁;孙丽萍;王志强;

• 1:平顶山市第二人民医院
• 2:郑州大学第一附属医院

摘要(Abstract)：

目的评价药物联合血管内Wingspan支架手术治疗颅内动脉狭窄的临床效果。方法颅内动脉狭窄患者168例,依据随机数字表法分成观察组和对照组,每组84例。对照组给予单纯药物治疗(如拜阿司匹林、波立维、立普妥),观察组在对照组基础上联合血管内Wingspan支架手术,比较2组患者随访中各时期卒中复发率、狭窄加重或复发情况。结果观察组随访中总卒中发生率、狭窄加重或复发概率均明显低于对照组,差异均有统计学意义(P<0.01);2组治疗后第1月神经功能改善情况比较差异无统计学意义(P>0.05);2组患者神经功能均于第4月后改善明显(P<0.01);观察组第4、7、10、13月神经功能改善情况明显优于对照组,差异有统计学意义(P<0.01)。结论药物联合血管内Wingspan支架手术能有效改善颅内动脉狭窄患者神经功能,防止卒中复发及狭窄加重或复发。

关键词(KeyWords)： Wingspan支架手术;颅内动脉狭窄;拜阿司匹林;神经功能;波立维

Abstract:

Keywords:

基金项目(Foundation): 2017年河南省医药卫生科技创新项目(编号：2017A0329)

作者(Author): 王彦阔;焦淑洁;孙丽萍;王志强;

Email:

DOI:

参考文献(References)：

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