非典型帕金森病的诊断和治疗
应浩杰;王运良;
摘要(Abstract)：
<正>根据英国脑库的诊断标准,帕金森病的定义为有运动迟缓表现且至少具有下列症状之一:静止性震颤、肌强直和姿势不稳。一旦病人出现帕金森病的症状,医生首先要考虑的问题是病人是否有帕金森病(PD)的常见原因或是非典型性帕金森病(AP)。虽然"非典型"的名称意味着PD的非典型表现,但多种疾病都可引起帕金森病。本文主要对3种特定的散发性非典型性帕金森病——进行性核上性麻痹(PSP)、皮质基底
关键词(KeyWords)： 非典型帕金森病;诊断;治疗
基金项目(Foundation):
作者(Authors): 应浩杰;王运良;
参考文献(References)：
- [1]Power BD,Jakabek D,Hunter-Dickson M,et al.Morphometric analysis of thalamic volume in progressive supranuclear palsy:In vivo evidence of regionally specific bilateral thalamic atrophy[J].Psychiatry Res,2017,265:65-71.
- [2]Ling H.Clinical Approach to Progressive Supranuclear Palsy[J].J Mov Disord,2016,9(1):3-13.
- [3]Armstrong MJ,Litvan I,Lang AE,et al.Criteria for the diagnosis of corticobasal degeneration[J].Neurology,2013,80(5):496-503.
- [4]Niethammer M,Tang CC,Feigin A,et al.A disease-specific metabolic brain network associated with corticobasal degeneration[J].Brain,2014,137(11):3 036-3 046.
- [5]Stefanova N,Wenning GK.Multiple system atrophy:emerging targets for interventional therapies[J].Neuropatholo Applied Neurobiol,2016,42(1):20-32.
- [6]Palma JA,Kaufmann H.Novel Therapeutic approaches in multiple system atrophy[J].Clin Auton Res,2015,25(1):37-45.
- [7]Coon EA,Sletten DM,Suarez MD,et al.Clinical features and autonomic testing predict survival in multiple system atrophy[J].Brain,2015,138(12):3 623-3 631.
- [8]Ubhi K,Low P,Masliah E.Multiple System Atrophy:A Clinical andNeuropathological Perspective[J].Trends Neurosci,2011,34(11):581-590.