早期进展性卒中诊断与病因机制
耿学川,盖红,杜继臣
摘要(Abstract)：
<正>早期进展在缺血性卒中中较为常见,其潜在的发病机制仍不太明确,国外学者认为脑卒中后早期神经功能障碍的进展性加重是由于梗死本身机制的作用,最终引起缺血半暗带和缺血区周围正常脑组织进一步损伤的结果[1]。
关键词(KeyWords)： 进展性卒中;病因;诊断
基金项目(Foundation):
作者(Author): 耿学川,盖红,杜继臣
参考文献(References)：
- [1]Karepov VG,Gur AY,Bova I,et al.Stroke-in-evolution:Infarct-inherent mechanisms versus systemic causes[J].Ce-rebrovasc Dis,2006,21(1/2):42-46.
- [2]Birschel P,Ellul J,Barer D.On behalf of the European pro-gressing stroke study(EPSS)group:progressing stroke:To-wards an internationaly agreed definition[J].Cerebrovase Dis,2004,17(2/3):242-252.
- [3]付海龙,吕晓红.进展性缺血性脑卒中诊断与相关因素的研究[J].中风与神经疾病杂志,2008,25(1):123.
- [4]Tei H,Uchiyama S,Ohara K,et al.Deteriorating ischemicstroke in 4 clinical categories classified by the OxfordshireCommunity Stroke Project[J].Stroke,2000,31:2 049-2 054.
- [5]Kwan J,Hand P.Early neurological deterioration in acutestroke:clinical characteristics and impact on outcome[J].QJM,2006,99:625-633.
- [6]Caplan LR.Worsening in ischemic stroke patients:is it timefor a new strategy?[J].Stroke,2002,33:1 443-1 445.
- [7]Pulsinelli W.Pathophysiology of acute ischaemic stroke[J].Lancet,1992,339:533-536.
- [8]Toni D,De Michele M,Fiorelli M,et al.Influence of hyper-glycaemia on infarct size and clinical outcome of acute ischemicstroke patients with intracranial arterial occlusion[J].J Neu-rol Sci,1994,123:129-133.
- [9]Ali LK,Saver JL.The ischemic stroke patient who worsens:new assessment and management approaches[J].Rev NeurolDis,2007,4:85-91.
- [10]贾志斌,李卫军,李靖.进展性卒中的临床探讨[J].中国实用神经疾病杂志,2010,13(10):15-16.
- [11]孟江涛,高玉林.进展性缺血性卒中的研究近况[J].中国民康医学杂志,2006,18(5):392.
- [12]Schellinger PD,Fiebach JB,Jansen O,et al.Stroke magneticresonance imaging within 6 hours after onset of hyperacutecerebral ischemia[J].Ann Neurol,2001,49:460-469.
- [13]Rajajee V,Kidwell C,Starkman S,et al.Early MRI and out-comes of untreated patients with mild or improving ischemicstroke[J].Neurology,2006,67:980-984.
- [14]Kang DW,Latour LL,Chalela JA,et al.Early ischemic le-sion recurrence within a week after acute ischemic stroke[J].Ann Neurol,2003,54:66-74.
- [15]Weimar C,Mieck T,Buchthal J,et al for the German StrokeStudy Collaboration.Neurologic worsening during the acutephase of ischemic stroke[J].Arch Neurol,2005,62:393-397.
- [16]Oppenheim C,Samson Y,Manai R,et al.Prediction of ma-lignant middle cerebral artery infarction by diffusion-weightedimaging[J].Stroke,2000,31:2 175-2 181.
- [17]Larrue V,von Kummer R,del Zoppo G,et al.Hemorrhagictransformation in acute ischemic stroke.Potential contribu-ting factors in the European Cooperative Acute Stroke Study[J].Stroke,1997,28:957-960.
- [18]Rubiera M,Alvarez-Sab n J,Ribo M,et al.Predictors ofearly arterial reocclusion after tissue plasminogen activator-in-duced recanalization in acute ischemic stroke[J].Stroke,2005,36:1 452-1 456.
- [19]Bogousslavsky J,Martin R,Regli F,et al.Persistent worse-ning of stroke sequelae after delayed seizures[J].Arch Neu-rol,1992,49:385-388.