闫文军,黄丽娜,富奇志,连立飞,杜敢琴

• 1:河南科技大学第一附属医院神经内科

摘要(Abstract)：

目的研究缺血性脑白质病变患者认知功能障碍的发病率及相关危险因素。方法收集75例脑白质病变(white matter lesions,WML)患者的人口学资料和血管危险因素,并进行认知功能评定,将病例分为认知障碍组和对照组,2组对比研究,探讨WML患者认知障碍的可能危险因素。结果 75例患者中44例(58.7%)出现了不同程度的认知功能障碍。Logistic回归分析显示WML患者发生认知功能障碍与高血压(OR 4.050,95%CI 1.309～12.526)、糖尿病(OR 3.820,95%CI 1.103～13.231)和年龄(OR 1.133,95%CI 1.023～1.255)有关。结论较高比例WML患者可出现认知功能障碍,高血压、糖尿病和老龄与认知功能障碍的发生关系密切。

关键词(KeyWords)： 脑白质病变;认知功能障碍;危险因素

Abstract:

Keywords:

基金项目(Foundation): 河南省洛阳市卫生局科技攻关计划资金项目(0901066A)

作者(Author): 闫文军,黄丽娜,富奇志,连立飞,杜敢琴

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