非痴呆型血管性认知障碍的临床分析
赵少荣,张晓虹
摘要(Abstract):
目的探讨各种类型脑血管病:如脑梗死、脑出血和皮质下白质缺血等引起的非痴呆型血管性认知障碍(VCIND)。方法收集2006-05~2011-05就诊的179例各种脑血管病后3个月内患者,随机选取100例脑血管病人作为研究对象,测定其认知功能进行MMSE、CDR评分,同时收集相同时期仅有高血压、糖尿病、冠心病等脑血管病危险因素而无脑血管病者96例。结果脑血管病组检出VCIND者39例,仅有危险因素而无卒中者检出VCIND 9例。结论脑血管病后3个月内VCIND发生率远大于仅有危险因素无卒中者,与报道的相一致。
关键词(KeyWords): VCIND;脑血管病;脑血管病危险因素
基金项目(Foundation):
作者(Author): 赵少荣,张晓虹
参考文献(References):
- [1]Gorelick PB,Bowler JV.Advances in vascular cognitive impair-ment[J].Stroke,2010,41:93-98.
- [2]血管性认知功能损害专家共识组.血管性认知功能损害专家共识[J].中华内科杂志,2007,46:1 052-1 055.
- [3]Zekry D.Is it possible to treat vascular cementia[J].FrontNeurol Neurosci,2009,24:95-106.
- [4]Sorrentino G,Migliaccio R,Bonavita V.Treatment of vasculardementia:the route of prevention[J].Eur Neurol,2008,60:217-223.
- [5]Moorhouse P,Rockwood K.Vascular cognitive impairment:current concepts and clinical developments[J].Lancet Neurol,2008,17:246-255.
- [6]Ishii H,Meguro K,Yamaguchi S,et al.Prevalence and cogni-tive performances of vascular cognitive impairment no dementiain Japan:the Osaki-Tajiri Project[J].Eur J Neurol,2007,14:609-616.
- [7]Frisoni GB,Galluzzi S,BrescianiL,et al.Mild cognitive impair-ment with subcortical vascular featutes:clinica characterisiticsand outcome[J].J Neurol,2002,249:1 423-1 423.
- [8]Stephens S,Kenny RA,Rowan E,et al.Neuropsychologicalcharacteristics ofmild vascular cognitive impairment and demen-tia after stroke[J].Int J Geriatr Psychiatry,2004,19:1 053-1057.
- [9]Wright CB,Festa JR,Paik MC,et al.White matter hyperin-tensities and subclinical infarction:association with psychomo-tor speed and cognitive flexibility[J].Stroke,2008,39:800-805.
- [10]Deland-wood L,Abeles N,Sacco JM,et al.Regional whitematter pathology in mild cognitive impairment:differential in-fluence of lesion type on neuropsychological functioning[J].Stroke,2008,39:794-799.
- [11]朱穆峰.非痴呆型血管性认知障碍[J].国际脑血管病杂志,2010,18(11):841.