姚晓腾,荆国杰,谢乙团,李毅毅,陈佳,景英朝,曾春生,林才

• 1:广东惠州市第一人民医院神经外科

摘要(Abstract)：

目的观察重型颅脑损伤患者BPC、D-dimer、FIB的变化及与亚低温治疗预后的关系,并探讨重型颅脑损伤患者亚低温治疗的准入指标。方法收集重型颅脑损伤患者68例,随机分为亚低温治疗组及常温治疗组,2组患者除低温相关干预措施不同外,其余治疗方案均相同。治疗时观察分析各患者BPC、D-dimer、FIB变化与预后的相关性。结果 FIB在伤后6 h内,D-dimer在伤后12 h内均出现异常增高,两者在亚低温治疗患者上升程度均较常温组低,随后出现下降趋势。亚低温组无需血小板治疗者的疗效较需输注血小板治疗者好(P=0.000)。结论在颅脑损伤后6 h内开始实施亚低温治疗可以改善预后。曾发BPC<50×109/L患者,预后差,可作为评价预后的指标之一。

关键词(KeyWords)： 亚低温;凝血功能;血小板;准入指标

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 姚晓腾,荆国杰,谢乙团,李毅毅,陈佳,景英朝,曾春生,林才

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