婴幼儿良性惊厥32例临床分析及血清神经元特异性烯醇化酶测定
李春香,崔焕芹,柳雪梅,李树松
摘要(Abstract)：
目的研究轻度胃肠炎并婴幼儿良性惊厥的临床特点及中枢神经元的损伤情况。方法收集2008-11～2010-01我院诊断轻度胃肠炎并婴幼儿良性惊厥的32例患儿作为观察组,记录患儿的胃肠炎表现及惊厥特点,随访6月以上。应用Elecsys 2010电化学发光免疫分析仪检测血清NSE水平。对照组20例,为同期我院门诊健康体检者。结果患儿胃肠炎均较轻,仅11例伴有轻度脱水,无电解质紊乱,大多惊厥频繁可成簇发作,最多者惊厥达5次,发作形式多为强直或强直阵挛,仅6例伴双目向一侧斜视。发作间期脑电图多正常,有7例见散在癫样放电,影像学检查均未见异常。该病预后良好,31例随访期间未再出现惊厥,仅1例因再次轻度胃肠炎并婴幼儿良性惊厥出现惊厥复发。观察组NSE高于正常对照组(P<0.01)。结论轻度胃肠炎并婴幼儿良性惊厥胃肠炎表现均轻微,惊厥往往成簇发作;发作间期脑电图多正常;可对神经元造成损伤;预后良好。
关键词(KeyWords)： 胃肠炎;惊厥;婴幼儿;神经元特异性烯醇化酶
基金项目(Foundation):
作者(Author): 李春香,崔焕芹,柳雪梅,李树松
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