丁螺环酮治疗脑梗死后抑郁疗效观察
陈瑛
摘要(Abstract):
目的观察丁螺环酮治疗脑梗死后抑郁的临床疗效。方法 86例脑梗死后抑郁患者分为干预组(42例)和对照组(44例),干预组给予丁螺环酮口服,对照组给予安慰剂,8周为1疗程。治疗前后采用汉密尔顿抑郁(HAMD)量表进行评分来判断治疗效果,采用TESS量表来判断不良反应情况。结果丁螺环酮治疗脑梗死后抑郁总有效率高于对照组,但差异无统计学意义(P>0.05),干预组不良反应发生率明显高于对照组(P<0.05)。结论脑梗死后抑郁宜以非药物治疗为主。
关键词(KeyWords): 脑梗死后抑郁;丁螺环酮;随机对照试验
基金项目(Foundation):
作者(Author): 陈瑛
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