急性脑梗死患者血清IL-17动态改变的临床研究Clinical study on dynamic change of serum interleukin-17 levels in patients with acute cerebral infarction
邵可可,荣良群,魏秀娥
摘要(Abstract)：
目的动态观察急性脑梗死患者血清白介素-17(Interleukin-17 IL-17)含量变化,探讨IL-17在脑梗死发病机制中的作用。方法采用酶联免疫吸附法(ELISA)动态检测46例急性脑梗死患者和21例健康对照者的血清IL-17浓度值。结果急性脑梗死患者发病后1 d、3 d、7 d和14 d时血清IL-17浓度明显高于对照组,差异有统计学意义(P<0.01)。不同时间组之间比较差异有统计学意义(P<0.01),其中发病3 d水平最高,随时间推移及治疗的介入,IL-17水平逐渐下降。结论急性脑梗死患者血清IL-17水平明显升高,动态观察患者的IL-17含量变化可能有助于监测急性脑梗死的病情变化。
关键词(KeyWords)： 急性脑梗死;白细胞介素17;酶联免疫吸附
基金项目(Foundation):
作者(Author): 邵可可,荣良群,魏秀娥
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