家属协同延续性护理模式联合音乐疗法对阿尔茨海默病患者生活质量的影响Effect of family collaborative continuous nursing mode combined with music therapy on quality of life of patients with Alzheimer's disease
王亚军;张环环;陈明明;杨俊娜;王艳艳;余金雪;王朝娟;郭世燕;
摘要(Abstract):
目的 探讨阿尔茨海默病患者治疗过程中以家属协同延续性护理联合音乐疗法,对其生活质量的影响。方法 纳入研究的70例阿尔茨海默病患者,均选自2020-01—2021-01在河南科技大学第一附属医院行对照治疗的患者,对照组35例采用常规护理,观察组35例采用家属协同延续性护理模式联合音乐疗法。分别以生活能力量表(ADL)及精神量表(MMSE)、焦虑量表(SAS)、抑郁量表(SDS)、生活质量量表(SF-36)为基准,评定2组患者干预前后的生活能力、精神状态、负面情绪、生活质量数据。比较2组的满意度。结果 干预前2组患者的ADL及MMSE评分无统计学差异(P>0.05);干预后观察组患者的ADL及MMSE评分较对照组优,差异有统计学意义(P<0.05)。干预前2组患者的SDS、SF-36等评分差异无统计学意义(P>0.05);干预后观察组患者的SDS、SF-36(生活质量量表)等评分比对照组优,差异有统计学意义(P<0.05)。满意度数据观察组(94.28%)较对照组(82.85%)高(P<0.05)。结论 对阿尔茨海默病患者采用家属协同延续性护理模式联合音乐疗法,可起到稳定患者情绪,改善患者精神状态及提高生活质量的效果。
关键词(KeyWords): 阿尔茨海默病;负面情绪;精神状态;生活质量;音乐疗法;家属协同延续性护理
基金项目(Foundation): 河南省科技攻关项目(编号:162102310415)
作者(Authors): 王亚军;张环环;陈明明;杨俊娜;王艳艳;余金雪;王朝娟;郭世燕;
参考文献(References):
- [1]刘玉花.对阿尔茨海默病患者采用综合护理干预的效果分析[J].中国医药指南,2017,15(6):235-236.
- [2]GREEN R C,CHRISTENSEN K D,CUPPLES L A,et al.A randomizednon inferiority trial of condensed protocols for genetic risk disclosure of Alzheimer’s disease[J].Alzheimers Dement,2015,11(10):1222-1230.
- [3]WEINER M W,VEITCH D P,AISEN P S,et al.Recent publications from the Alzheimer’s Disease Neuroimaging Initiative:Reviewing progress toward improved AD clinical trials[J].Alzheimers Dement,2017,13(4):e1-e85.
- [4]钱来,秦若梦,赵辉.阿尔茨海默病患者认知域与脑皮层下结构体积的相关性研究[J].中国实用神经疾病杂志,2021,24(12):1013-1019.
- [5]张营丽,周艳华,李卓,等.正念冥想疗法干预阿尔茨海默病患者神经损伤及焦虑抑郁的效果分析[J].中国实用神经疾病杂志,2020,23(20):1813-1817.
- [6]JIAO B,TANG B,LIU X,et al.Mutational analysis in early onset familial Alzheimer’s disease in mainland China[J].Neurobiol Aging,2014,35:1957.e1-19576.e
- [7]JIANG H Y,LI G D,DAI S X,et al Identification of PSEN1 mutations p.M233L and p.R352C in Han Chinese families with early onsetfamilial Alzheimer’s disease[J].Neurobiol Aging,2015,36:1602.e3-6.
- [8]ZHANG H R,PENG J H,CHENG X B,et al.Paeoniflorin attenuates amyloidogenesis and the inflammatory responses in a transgenic mousemodel of Alzheimer’s disease[J].Neurochem Res,2015,40(8):1583-1592.
- [9]张营丽,周艳华,李卓,等.生酮饮食对阿尔茨海默病患者神经损伤及焦虑抑郁情绪的影响[J].中国实用神经疾病杂志,2021,24(1):49-53.
- [10]DAVIS R,OHMAN J.Wayfinding in ageing and Alzheimer’s disease within a virtual senior residence:study protocol[J].JAdvanced Nursing,2016,72(7):1677.
- [11]KIMZEY M,MASTELSMITH B,ALFRED D.The impact of educational experiences on nursing students‘knowledge and attitudes toward people with Alzheimer’s disease:A mixed method study[J].Nurs Educ Today,2016,46(12):57-63.
- [12]NIELSEN A B S,SIERSMA V,WALDEMAR G,et al.Poor self rated health did not increase risk of permanent nursing placement or mortality in people with mild Alzheimer’s disease[J].BMC Geriatr,2016,16(1):1-8.
- [13]YANG Y H,WU M N,CHOU P S,et al.Longitudinal Neuropsychological Outcome in Taiwanese Alzheimer’s Disease Patients Treated with Medication[J].Curr Alzheimer Res,2018,15(5):474-481.
- [14]RUBBI I,MAGNANI D,NALDONI G,et al.Efficacy of video-music therapy on quality of life improvement in a group of patients with Alzheimer’s disease:a pre-post study[J].Acta Biomed,2016,87(4-S):30-37.
- [15]PARK S C,JANG E Y,KIM D,et al.Dimensional approach to symptom factors of major depressive disorder in Koreans,using the Brief Psychiatric Rating Scale:the Clinical Research Center for Depression of South Korea study[J].Kaohsiung J Med Sci,2015,31(1):47-54.
- [16]KNOPMAN D S,CASELLI R J.Appraisal of cognition in preclinical Alzheimer’s disease:a conceptual review[J].Neurodegener Dis,2012,2(2):183-195.
- [17]MASEDA A,SáNCHEZ A,MARANTE M P,et al.Multisensory stimulation on mood,behavior,and biomedical parameters in people with dementia:is it more effective than conventional one-to-one stimulation?[J].Am J Alzheimer’s Dis Other Demen,2014,29(7):637-647.
- [18]SáNCHEZ A,MASEDA A,MARANTE-MOAR M P,et al.Comparing the effects of multisensory stimulation and individualized music sessions on elderly people with severe dementia:a randomized controlled trial[J].J Alzheimer’s Dis,2016,52(1):303-315.
- [19]MASEDA A,SáNCHEZ A,MARANTE M P,et al.Effects of multisensory stimulation on a sample of institutionalized elderly people with dementia diagnosis:a controlled longitudinal trial[J].Am J Alzheimer’s Dis Other Demen,2014,29(5):463-473.
- [20]BEI L,SHUI Y B,BAI F,et al.A test of lens opacity as an indicator of preclinical Alzheimer Disease[J].Exp Eye Res,2015,140:117-123.
- [21]ARMSTRONG R,KERGOAT H.Oculo-visual changes and clinical considerations affecting older patients with dementia[J].Ophthalmic Physiol Opt,2015,35(4):352-376.
- [22]BUSH A I.Drug development based on the metals hypothesis of Alzheimer’s disease[J].J Alzheimers Dis,2008,15(2):223-240.
- [23]RISACHER S L,WUDUNN D,PEPIN S M,et al.Visual contrast sensitivity in Alzheimer’s disease,mild cognitive impairment,and older adults with cognitive complaints[J].Neurobiol Aging,2013,34(4):1133-1144.
- [24]VELAYUDHAN L,LOVESTONE S.Smell identification test as a treatment response marker in patients with Alzheimer disease receiving donepezil[J].J Clin Psychopharmacol,2009,29(4):387-390.
- [25]AYALA-GROSSO C A,PIERUZZINI R,DIAZ-SOLANO D,et al.Amyloid-A β peptide in olfactory mucosa and mesenchymal stromal cells of mild cognitive impairment and Alzheimer’s disease patients[J].Brain Pathol,2015,25(2):136-145.
- [26]DEVANAND D P,LEE S,MANLY J,et al.Olfactory deficits predict cognitive decline and Alzheimer dementia in an urban community[J].Neurology,2015,84(2):182-189.
- [27]WU N,RAO X P,GAO Y L,et al.Amyloid-β deposition and olfactory dysfunction in an Alzheimer’s disease model[J].J Alzheimer’s Dis,2013,37(4):699-712.
- [28]YAN Z,FENG J.Alzheimer’s disease:interactions between cholinergic functions and beta-amyloid[J].Curr Alzheimer Res,2004,1(4):241-248.
- [29]SUNDERMANN E E,GILBERT P E,MURPHY C.The effect of hormone therapy on olfactory sensitivity is dependent on apolipoprotein E genotype[J].Horm Behav,2008,54(4):528-533.
- [30]ONIEVA-ZAFRA M D,HERNáNDEZ-GARCIA L,GONZA-LEZDEL-VALLE M T,et al.Music intervention with reminiscence therapy and reality orientation for elderly people with Alzheimer disease living in a nursing home:a pilot study[J].Holist Nurs Pract,2018,32(1):43-50.
- [31]HOUSTON M.Multi-sensory stimulation environments for use with dementia patients:staff perspectives on reduction of agitation and negative behaviors[D].Burlingbon:The University of Vermont and State Agricultural College,2015.
- [32]CRUZ J,MARQUES A,BARBOSA A L,et al.Effects of a motor and multisensory-based approach on residents with moderate-tosevere dementia[J].Am J Alzheimer’s Dis Other Demen,2011,26(4):282-289.
- [33]MCDERMOTT O,CRELLIN N,RIDDER H M,et al.Music therapy in dementia:a narrative synthesis systematic review[J].Int J Geriatr Psychiatry,2013,28(8):781-794.
- [34]RAGLIO A,FILIPPI S,BELLANDI D,et al.Global music approach to persons with dementia:evidence and practice[J].Clin Interv Aging,2014,6(9):1669-1678.
- [35]THAL D R,VON ARNIM C,GRIFFIN W S T,et al.Pathology of clinical and preclinical Alzheimer’s disease[J].Eur Arch Psychiatry Clin Neurosci,2013,263(2):137-145.
- [36]PUDELEWICZ A,TALARSKA D,B?CZYK G.Burden of caregivers of patients with Alzheimer’s disease[J].Scand J Caring Sci,2019,33(2):336-341.DOI:10.1111/scs.12626.
- [37]ALJEZAWI M,AL QADIRE M,SULIMAN M,et al.Undergraduate nursing students’knowledge of and attitudes toward people with alzheimer’s Disease[J].BMC Geriatr,2022,22(1):691.DOI:10.1186/s12877-022-03389-6.
- [38]WANG L Y,YANG R,HU X Y,et al.Construction of Graded Nursing Care Index System for Patients With Alzheimer’s Disease[J].Hu Li Za Zhi,2020,67(1):98-105.Doi:10.6224/JN.202002_67(1).12.
- [39]SCHERDER E,VAN MANEN F.Pain in Alzheimer’s disease:nursing assistants’and patients’evaluations[J].J Adv Nurs,2005,52(2):151-8.DOI:10.1111/j.1365-2648.2005.03577.x.
- [40]GANZER C A.Assessing Alzheimer’s disease and dementia:best practices in nursing care[J].Geriatr Nurs,2007,28(6):358-365.DOI:10.1016/j.gerinurse.2007.10.008.
- [41]BECK C,HEACOCK P.Nursing interventions for patients with Alzheimer’s Disease[J].Nurs Clin North Am,1988,23(1):95-124.
- [42]SCHUTTE D L.Genetic testing and Alzheimer’s disease:implications for psychiatric-mental health nursing[J].J Psychosoc Nurs Ment Health Serv,2013,51(11):14-8.DOI:10.3928/02793695-20131010-01.
- [43]Chen X,Li L,Sharma A,Dhiman G,Vimal S.The Application of Convolutional Neural Network Model in Diagnosis and Nursing of MR Imaging in Alzheimer’s Disease[J].Interdiscip Sci,2022,14(1):34-44.DOI:10.1007/s12539-021-00450-7.
- [44]AMOUYAL-BARKATE K,VOISIN T,ANDRIEU S,et al.Stratégie soignante.Alzheimer,diagnostic précoce et thérapeutiques Nursing strategy.Alzheimer’s disease,early diagnosis and treatments[J].Soins Gerontol,2002,(36):14-21.
- [45]MCNAIR T.Early Intervention for Caregivers of Patients With Alzheimer’s Disease[J].Home Healthc Now,2015,33(8):425-30.DOI:10.1097/NHH.0000000000000279.
- [46]BONNEL W.Becoming part of the plan to help conquer Alzheimer’s disease:the national Alzheimer’s project act[J].JGerontol Nurs,2013,39(8):9-11.DOI:10.3928/00989134-20130530-02.
- [47]BAUDY M.Réflexionéthique sur la prise en charge du patient atteint de la maladie d’Alzheimer Ethical considerations on care of the patient with Alzheimer disease[J].Soins Gerontol,2009,(80):35-36.