颅内动脉瘤破裂的临床特点及相关危险因素探讨Clinical characteristic and risk factors for intracranial aneurysm rupture
荆国杰,姚晓腾,祝刚,谢乙团,景英朝,马宝新,李毅毅,曾春生
摘要(Abstract)：
目的探讨未破裂颅内动脉瘤发生破裂的临床特点及相关危险因素。方法对184例颅内动脉瘤患者的临床资料采用卡方检验及Logistic多元回归模型,对破裂组(150例)和未破裂组(34例)各相关危险因素进行统计学分析。结果颅内动脉瘤破裂出血的首发症状多为头痛(82.0%)、头晕(81.3%),多见于40~60岁,男∶女为1∶1.2。以ACA最常见,AComA其次,ICA最低。单因素分析表明,年龄(P=0.010)、吸烟(P=0.032)、嗜酒(P=0.038)、糖尿病(P=0.022)、瘤直径的大小(P=0.040)与颅内动脉瘤破裂有显著相关性;多因素Logistic分析结果显示,年龄、糖尿病是动脉瘤破裂的独立危险因素。结论颅内动脉瘤破裂好发于40~60岁,首发症状以头痛、头晕为主。年龄、糖尿病是动脉瘤破裂的危险因素。年龄≤60岁可增加动脉瘤破裂的风险,相反,糖尿病能降低动脉瘤破裂的风险。
关键词(KeyWords)： 颅内动脉瘤;破裂;危险因素;蛛网膜下腔出血
基金项目(Foundation):
作者(Author): 荆国杰,姚晓腾,祝刚,谢乙团,景英朝,马宝新,李毅毅,曾春生
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