脑梗死患者颈动脉斑块与血尿酸水平的相关性研究Relationship between serum uric acid and carotid artery plaque in patients with cerebral infarction
顾汉沛,陈孝东,王光胜,耿德勤
摘要(Abstract)：
目的通过分析脑梗死患者血清尿酸(UA)水平与颈动脉斑块发生的关系,探讨血清UA在动脉粥样硬化疾病早期预防中的价值。方法 209例连续住院脑梗死患者,测定外周血尿酸水平,用颈动脉超声检查颈动脉斑块。结果检查209例患者中,发现颈动脉斑块166例(79.43%),男119例(71.7%),女47例(28.3%);无斑块组男22例(51.2%),女21例(48.8%);血尿酸均值斑块组(321.89±94.59)μmmol/L,明显高于无斑块组(254.07±77.06)μmmol/L(P<0.01);调整年龄、吸烟、高胆固醇、高甘油三酯、高血压、糖尿病等因素,血尿酸是颈动脉斑块的独立危险因素,OR值为1.008(P=0.009,95%CI=1.002～1.013)。结论在脑梗死患者颈动脉粥样硬化斑块形成的过程中,血UA水平起重要作用。
关键词(KeyWords)： 动脉粥样硬化斑块;血尿酸;脑梗死
基金项目(Foundation):
作者(Author): 顾汉沛,陈孝东,王光胜,耿德勤
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