桥本脑病的临床及脑电图动态观察
吴海香,杨清成,张向东,安晶
摘要(Abstract):
目的研究桥本脑病的临床及脑电图特点以提高对本病的诊治水平。方法本文对1例桥本脑病患者的临床及脑电图进行动态观察,同时进行文献复习。结果桥本脑病脑电图具有特征性表现:弥漫性慢波,可见癫波、三相波。结论脑电图对本病有诊断、鉴别诊断的价值。
关键词(KeyWords): 桥本脑病;抗甲状腺抗体;脑电图
基金项目(Foundation):
作者(Author): 吴海香,杨清成,张向东,安晶
参考文献(References):
- [1]Brain L,Jellinek EH,Ball KI.Hashimoto’s disease and en-cephalopathy[J].Lancet,1966,2:512-514.
- [2]Ferracci F,Bertiato G,Moretto G.Hashimoto’s encephalopa-thy:epidemiologic data and pathogenetic considerations[J].JNeurol Sci,2004,217:165-168.
- [3]Chong JY,Rowland LP,Utiger RD.Hasimoto encephalopa-thy:syndrome or myth[J].Arch Neurol,2003,2:164-171.
- [4]Kothbauer-Margreiter I,Sturzenegger M,Komor J,et al.en-组别n性别男女年龄/岁<1 1~2>2~3>3~4>4农村/城市最高体温(℃)均值恶心呕吐[例(%)]惊颤[例(%)]恶心、呕吐、惊颤同时存在[例(%)]对照组347 228 119 11 104 208 17 7 146/201 38.7 102(29)288(83)45(12.9)观察组23 15 8 1 6 13 2 1 16/7 39 21(91.3)18(78.2)22(95.6)表2 2组患儿血常规、血糖比较[例(%)]组别n血常规(4~10)×109/L(10~15)×109/L>15×109/L<4×109/L血糖正常升高对照组347 195(56.1)102(29.4)28(8)22(6.2)301(86.7)46(13.2)观察组23 13(56.5)6(26.0)2(8.6)2(8.6)19(82.6)4(17.3)cephalopathy assoeiated with Hashimoto thyroiditis:diagnosisand treatment[J].Neurol,1996,8:585-593.
- [5]李湘青,王宪玲.桥本脑病6例临床分析[J].中国实用神经疾病杂志,2010,13(3):49-52.
- [6]Castillo P,Woodruff B,Caselli R.Steroid-responsive encepha-lopathy associated with autoimmune thyroiditis[J].Arch Neu-rol,2006,63:197-202.
- [7]Schauble B,Castillo PR,Boeve BF,et al.EEG findings in ster-oid responsive encephalopathy associated with autoimmune thy-roiditis[J].Clin Neurophysiol,2003,1:32-37.
- [8]Henchey R,Cibula J,Helveston W,et al.Electroencephalo-graphic findings in Hashimoto’s encephalopathy[J].Neurolo-gy,1995,5:977-981.
- [9]Peschen-Rosin R,Schabet M,Dichgans J.Manifestation ofHashimoto’s encephalopathy years before onset of thyroid dis-ease[J].Eur Neurol,1999,2:79-84.